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Cause and possible relief of cancer bone pain
Scientist reports discovering a key pathway that drives cancer-related bone pain while providing a potential solution with a drug that already is on the market.
Immunotherapy target suppresses pain to mask cancer
Researchers found that a molecule called PD-L1, which is blocked by the immunotherapy drug nivolumab, acts not only on immune cells but also on the nerve cells that signal pain. That insight could lead to a simple test that measures subtle differences in pain sensitivit...
Unexpected mechanism behind chronic nerve pain
It has long been assumed that chronic nerve pain is caused by hypersensitivity in the neurons that transmit pain. Researchers now show that another kind of neuron that normally allows us to feel pleasant touch sensation can switch function and instead signal pain after ...
Certain immune reactions to viruses cause learning problems
Researchers have discovered a mechanism by which the body's immune reaction to viruses like influenza and HIV may cause learning and memory problems.